Peptide Database

Peptide NameGlycoprotein hormones alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC454H716N132O137S13

DescriptionStandard

        YPNNEMARGGCDECRLQENKIFSKPSAPIFQCVGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAREVTRLDNMKLENHTDCHCSTCYYHKF
    

Molecular Weight10632.19 Da

Isoelectric Point (pI)8.57

Net Charge (pH 7.0)3.93

Net Charge (pH 7.4) 3.40

Charge Density (pH 7.0) 0.0423

GRAVY Index-0.53

Hydrophobic Moment 0.68

Boman Index-0.13

Instability Index52.08

Aliphatic Index 51.40

Aromaticity 0.0860

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4351.69

LogP -49.26

H-bond Donors 160.0

H-bond Acceptors 157.0

Rotatable Bonds 347.0

Heavy Atoms 736.0

Ring Count 17.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0295937 VERIFIED: YES

Provenance & Taxonomy

OrganismAnguilla anguilla [Animal]

FamilyGlycoprotein hormones

Tax ID7936

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-35; 14-64; 32-83; 36-85; 63-88

Other Mods56:N-linked (GlcNAc...) asparagine; 79:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min