Peptide Database

Peptide NameTCTP(I-9) I2A subsetution mutant

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC48H80N12O14S

DescriptionStandard

        MAIYRDLIS
    

Molecular Weight1081.29 Da

Isoelectric Point (pI)5.59

Net Charge (pH 7.0)-0.50

Net Charge (pH 7.4) -0.72

Charge Density (pH 7.0) -0.0555

GRAVY Index0.71

Hydrophobic Moment 0.45

Boman Index0.19

Instability Index3.81

Aliphatic Index 141.11

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 435.78

LogP -2.13

H-bond Donors 16.0

H-bond Acceptors 15.0

Rotatable Bonds 35.0

Heavy Atoms 75.0

Ring Count 1.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0380515 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTCTP

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorophore labeling

C-TermAmidation

Other ModsN-term detail: Rhodamine labeling

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHeLa

MethodFluorescence-based uptake assay

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