Peptide Database

Peptide NameTEWP

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antiviral

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC172H289N51O43S6

DescriptionStandard

        KKCPGRCTLKCGKHERPTLPYNCGKYICCVPVKVK
    

Molecular Weight3951.84 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.78

Net Charge (pH 7.4) 7.43

Charge Density (pH 7.0) 0.2223

GRAVY Index-0.53

Hydrophobic Moment 0.52

Boman Index-0.19

Instability Index32.22

Aliphatic Index 58.29

Aromaticity 0.0571

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1513.49

LogP -13.72

H-bond Donors 58.0

H-bond Acceptors 58.0

Rotatable Bonds 129.0

Heavy Atoms 272.0

Ring Count 7.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0015335 VERIFIED: YES

Provenance & Taxonomy

OrganismCaretta caretta [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermProglutamic acid block

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Anti-Gram-positive Anti-Gram-negative

TargetRhabdovirus

RECORD: Rec_0224431 VERIFIED: YES

Provenance & Taxonomy

OrganismCaretta caretta [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermProglutamic acid block

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Anti-Gram-positive Anti-Gram-negative

TargetSalmonella typhimurium

Activity2.8 μM

MethodIC50

RECORD: Rec_0226792 VERIFIED: YES

Provenance & Taxonomy

OrganismCaretta caretta [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermProglutamic acid block

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity3.3 μM

MethodIC50

RECORD: Rec_0230750 VERIFIED: YES

Provenance & Taxonomy

OrganismCaretta caretta [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermProglutamic acid block

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Anti-Gram-positive Anti-Gram-negative

TargetChandipura virus

RECORD: Rec_0403660 VERIFIED: YES

Provenance & Taxonomy

OrganismCaretta caretta [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermProglutamic acid block

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity5

MethodIC50