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MYP_013288
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antiviral
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
17 amino acids
C81H145N19O21
Standard
Sequence
ILGAILPLVSGLLSNKL
Physicochemical Analysis
1721.13 Da
8.75
0.76
0.55
0.0447
1.55
0.36
0.54
47.34
206.47
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
629.70
-3.04
21.0
22.0
57.0
121.0
1.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0278528 VERIFIED: NO
Provenance & Taxonomy
Alytes obstetricans [Animal]
Frog skin active peptide (FSAP)
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Hemolytic Non-ribosomal
Escherichia coli, Staphylococcus aureus
Qualitative functional evidence
PMID19463738 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19463738/; https://www.uniprot.org/uniprotkb/P0DQW6/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0334781 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0344650 VERIFIED: YES
Provenance & Taxonomy
European midwife toad [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperThe alyteserins: two families of antimicrobial peptides from the skin secretions of the midwife toad Alytes obstetricans (Alytidae).
RECORD: Rec_0414507 VERIFIED: YES
Provenance & Taxonomy
Alytes obstetricans [Plant]
Alyteserin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral
PaperPubMed PMID: 19463738 PMID19463738 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19463738/
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