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MYP_013279
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Basic Information
Brevinin-1PTb
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
24 amino acids
C112H188N28O27S3
Standard
Sequence
FMGGLIKAATKALPAAFCAITKKC
Physicochemical Analysis
2455.06 Da
9.70
3.74
3.50
0.1557
0.85
0.51
0.30
27.24
90.00
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
868.37
-6.00
32.0
34.0
81.0
170.0
3.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0188381 VERIFIED: YES
Provenance & Taxonomy
Hylarana picturata [Animal]
Brevinin
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0242550 VERIFIED: NO
Provenance & Taxonomy
Rana picturata,Hylarana picturata [Animal]; Hylarana signata [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus, Escherichia coli
RECORD: Rec_0289593 VERIFIED: YES
Provenance & Taxonomy
Spotted stream [Animal]
Brevinin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial
PMID18621071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18621071/
RECORD: Rec_0366610 VERIFIED: YES
Provenance & Taxonomy
Rana picturata [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25726
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ1815
RECORD: Rec_0380982 VERIFIED: YES
Provenance & Taxonomy
Rana picturata [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ1815
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