Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length479 amino acids

Chemical FormulaC2427H3874N624O672S15

DescriptionStandard

        MLLTGPSDKGEKMQKMWYSFLPCLLFLQLEANPGLKVRITQKGLDYGRKIGIELLKRRLLKETFPSWSGQESFSIVKVNYTISRFRVDAVDIPETSASFIPGTGVSLSVAHASAIISADWRVKTWLLKDQGGFTLSISELFIASVFKVSRDSTGHLSVLLHSCQLSIGSVKVKLNEGSSWIYSFLSGYLEKAIHSKLEENICLNIKYKIQMMDAQLRKQKVLSQIDAFAQIDYSLVSSPAVFKSHINLDLKGTVYPVGNHTDPPLVPAPFGLPSKGDSMLYLGVSSYFLKTATLAYYKAGVFNITISKDLATTFNLTTAMLKDFVPEIAPRCPTACPVLLKLMATSPPVVSLQSDTCRLWITGSVEVFAVLPNSTIQYIFTGNLTTSTRSNLTVIKQKLIISLLLKRLHFSLLHSAVRFSQVSLVENFLSYTLRRVVIPVINGKNYGQFLSTVGGKASLKPLKRVHSFKGCSVRSFLSV
    

Molecular Weight53027.47 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)24.22

Net Charge (pH 7.4) 23.34

Charge Density (pH 7.0) 0.0506

GRAVY Index0.19

Hydrophobic Moment 0.71

Boman Index0.13

Instability Index33.95

Aliphatic Index 105.37

Aromaticity 0.0960

Extinction Coeff. Reduced 55350.00

Extinction Coeff. Oxidized 55725.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0125656 VERIFIED: NO

Provenance & Taxonomy

OrganismMeleagris gallopavo [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria