Peptide Database

Peptide NameTGFβRII frameshift CTL epitope RLSSCVPVA

Function Ontology

Anticancer ▸ Tumor T-cell antigen

Immunology ▸ Epitope/vaccine antigen ▸ T-cell epitope

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC39H70N12O12S

DescriptionStandard

        RLSSCVPVA
    

Molecular Weight931.11 Da

Isoelectric Point (pI)8.25

Net Charge (pH 7.0)0.75

Net Charge (pH 7.4) 0.53

Charge Density (pH 7.0) 0.0834

GRAVY Index0.98

Hydrophobic Moment 0.35

Boman Index0.15

Instability Index100.93

Aliphatic Index 118.89

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 389.69

LogP -4.66

H-bond Donors 15.0

H-bond Acceptors 14.0

Rotatable Bonds 27.0

Heavy Atoms 64.0

Ring Count 1.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0157485 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytotoxic T-cell epitope Anticancer Immunomodulatory Tumor T-cell antigen T-cell epitope

TargetHLA-A*0201; HLA-A2-positive colon cancer cells with mutant TGFβRII

MethodHLA-A2-restricted CTL cytotoxicity assay