Peptide Database

Peptide NameSLAY-screened peptide P3888

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC33H53N7O12S

DescriptionStandard

        DPDPCII
    

Molecular Weight771.88 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.25

Net Charge (pH 7.4) -2.47

Charge Density (pH 7.0) -0.3211

GRAVY Index0.19

Hydrophobic Moment 0.22

Boman Index0.21

Instability Index-12.97

Aliphatic Index 111.43

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 294.94

LogP -1.71

H-bond Donors 9.0

H-bond Acceptors 11.0

Rotatable Bonds 20.0

Heavy Atoms 53.0

Ring Count 2.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0191649 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/