Peptide Database

Peptide NameHuman granulysin

Function Ontology

—

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC116H200N34O35S2

DescriptionStandard

        GRDYRTCLTIVQKLKKMVDTPTQ
    

Molecular Weight2695.17 Da

Isoelectric Point (pI)9.63

Net Charge (pH 7.0)2.75

Net Charge (pH 7.4) 2.52

Charge Density (pH 7.0) 0.1195

GRAVY Index-0.69

Hydrophobic Moment 0.66

Boman Index-0.25

Instability Index-2.66

Aliphatic Index 76.09

Aromaticity 0.0435

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1158.52

LogP -11.80

H-bond Donors 42.0

H-bond Acceptors 40.0

Rotatable Bonds 92.0

Heavy Atoms 187.0

Ring Count 2.0

Amide Bonds 24.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0278122 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)