Peptide Database

Peptide NameUnnamed

Function Ontology

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC114H174N30O30

DescriptionStandard

        KGKDKWIELKESWGAVWRID
    

Molecular Weight2444.78 Da

Isoelectric Point (pI)8.43

Net Charge (pH 7.0)0.77

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0384

GRAVY Index-0.98

Hydrophobic Moment 0.55

Boman Index-0.15

Instability Index14.69

Aliphatic Index 78.00

Aromaticity 0.1500

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 999.00

LogP -4.69

H-bond Donors 36.0

H-bond Acceptors 31.0

Rotatable Bonds 83.0

Heavy Atoms 174.0

Ring Count 6.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0118658 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-inflammatory

PaperBalachandran Manavalan et al. AIPpred: Sequence-Based Prediction of Anti-inflammatory Peptides Using Random Forest. Front Pharmacol. 2018. PMID: 29636690. https://pubmed.ncbi.nlm.nih.gov/29636690/ ; https://pmc.ncbi.nlm.nih.gov/articles/PMC5881105/ PMID29636690 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29636690/

RECORD: Rec_0432028 VERIFIED: YES

Provenance & Taxonomy

OrganismLolium perenne [Plant]

FamilyLol p 1-derived HLA-DR-binding peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

HLA class II binding

TargetHLA-DRB1*0101

Activity1666.7 nM

MethodHLA-DR binding affinity (IC50)

RECORD: Rec_0432029 VERIFIED: YES

Provenance & Taxonomy

OrganismLolium perenne [Plant]

FamilyLol p 1-derived HLA-DR-binding peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

HLA class II binding

TargetHLA-DRB1*0301

Activity>30000 nM

MethodHLA-DR binding affinity (IC50)

RECORD: Rec_0432030 VERIFIED: YES

Provenance & Taxonomy

OrganismLolium perenne [Plant]

FamilyLol p 1-derived HLA-DR-binding peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

HLA class II binding

TargetHLA-DRB1*0401

Activity3750.0 nM

MethodHLA-DR binding affinity (IC50)

RECORD: Rec_0432031 VERIFIED: YES

Provenance & Taxonomy

OrganismLolium perenne [Plant]

FamilyLol p 1-derived HLA-DR-binding peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

HLA class II binding

TargetHLA-DRB1*0404

Activity8333.3 nM

MethodHLA-DR binding affinity (IC50)