Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length228 amino acids

Chemical FormulaC1158H1754N260O344S9

DescriptionStandard

        IDDLAEVDYSLNSLPALFQPFIDLDLKGLVYPAGNYSGPPYVAAPFTIPDQGDSMLYLAFSEYFFQTCSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIVSLEQDSFTAEIQGSMEVFAVLPDSTTHSLFTMNIAANTSIALNIFDQKLMGSLCLNRLQFSLTHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight25110.43 Da

Isoelectric Point (pI)4.09

Net Charge (pH 7.0)-16.07

Net Charge (pH 7.4) -16.47

Charge Density (pH 7.0) -0.0705

GRAVY Index0.35

Hydrophobic Moment 0.55

Boman Index0.27

Instability Index44.15

Aliphatic Index 99.30

Aromaticity 0.1316

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0348809 VERIFIED: NO

Provenance & Taxonomy

OrganismOceanodroma tethys (Wedge-rumped storm-petrel) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria