Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length141 amino acids

Chemical FormulaC700H1127N197O188S8

DescriptionStandard

        PMALAMVHKPMLLLAITEFVANSAAFTYFTAGALHRNISSDMLPRRFPLQLKTKSMGLFSPQLQERYPNHPMELHLSARRQPLLSCRPDALHGTLFSSAEAFVVLPNATRIPAFLLNIDANMTGKPIITRNRLGGTVSLKG
    

Molecular Weight15567.16 Da

Isoelectric Point (pI)10.62

Net Charge (pH 7.0)8.39

Net Charge (pH 7.4) 8.05

Charge Density (pH 7.0) 0.0595

GRAVY Index0.08

Hydrophobic Moment 0.51

Boman Index0.09

Instability Index46.34

Aliphatic Index 95.60

Aromaticity 0.0709

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6079.06

LogP -55.92

H-bond Donors 211.0

H-bond Acceptors 209.0

Rotatable Bonds 504.0

Heavy Atoms 1093.0

Ring Count 27.0

Amide Bonds 151.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056829 VERIFIED: NO

Provenance & Taxonomy

OrganismDromas ardeola [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria