Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC411H644N120O114S

DescriptionStandard

        MSQYPELIAQFSSGNQTRIKQGLTAKAPLEGWRYGPKEIVKKFQIHHRVAIEYGGSVYDIDNLRIVTPRLHDEIHYRR
    

Molecular Weight9122.31 Da

Isoelectric Point (pI)9.63

Net Charge (pH 7.0)3.86

Net Charge (pH 7.4) 3.41

Charge Density (pH 7.0) 0.0494

GRAVY Index-0.66

Hydrophobic Moment 0.60

Boman Index-0.11

Instability Index49.18

Aliphatic Index 85.00

Aromaticity 0.1026

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 12950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3805.56

LogP -33.16

H-bond Donors 133.0

H-bond Acceptors 123.0

Rotatable Bonds 303.0

Heavy Atoms 646.0

Ring Count 17.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354798 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Nuclease Endonuclease Non-hemolytic Non-ribosomal