Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length246 amino acids

Chemical FormulaC1233H1886N304O334S12

DescriptionStandard

        MPLHRQVGTMFWYLLQMLFASLSQQVSTTAAAPLLHVSPSSQGEFYSLAKRFTVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYQKAGALVFEITEAMIPKEAGFRLDTSVFSAFIPQVSSLMYPNMPMKFRLSAPTAPFLTIGPGGISFQPIVDAQAYAILPNSSLVPLFLLSLVSLDTACGSGAGGSLSCAHHLLPQSARLGNDPWLLSPQHFLRFQCDQTKLLVSGKVCALATSLSLFLF
    

Molecular Weight26696.78 Da

Isoelectric Point (pI)8.37

Net Charge (pH 7.0)1.99

Net Charge (pH 7.4) 1.38

Charge Density (pH 7.0) 0.0081

GRAVY Index0.41

Hydrophobic Moment 0.53

Boman Index0.26

Instability Index45.60

Aliphatic Index 93.66

Aromaticity 0.1220

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21680.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0167351 VERIFIED: NO

Provenance & Taxonomy

OrganismFicedula albicollis (Collared flycatcher) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria