Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length577 amino acids

Chemical FormulaC2860H4550N756O876S10

DescriptionStandard

        MIITRANVDQYPWLPADIIRDIKLGYIVYDTETNEKSIRIEINCGVGLGACVKDKTSVVEDPSSTEKITITLPEYNLPWSSIPTLANSDSDKEIPPTKGGPSNDGVSPFNPNTKFKVNKPQKPVIISSNNNKLTNSSNNKELATNKGVMHFNGIVIEQLETFKKKYFLTKEAVNLVQDKLIESVISLYSKENSIDDNKVNSVNFMEFSEFDNNSFNEFDLMSTIPAENLINNSDLMSGELNKIAKNNGTVDVNARMAVIKENNKVIATLTRTDGVLVTKKVPVYEVNYAANSYHVDIKNMRIEYLLRPTSSPSGLGLQGNVIQNYSNENKKFSYPEKVELPNKAENKRIDAPYPHQFNDAIIVFPKNSNLPPLYAYSGFPAIELKDKDPRPQQEKEFNDIKGGVKFTISFYEKVTQEFGKKAAQLSRELAEQSKGKTIRNVEDALRTYEKYGQNINNKINAKDRAAIIKALESIDAKQLASNLGKFSKGLGYTNHAINAVELLVEFNKAVKTGNWRPFFVKATAITAGMAAVALTAFSFSLIIGGPVGILGYALIIATVGALIDDALVEKVSSEIGI
    

Molecular Weight63861.91 Da

Isoelectric Point (pI)8.08

Net Charge (pH 7.0)1.90

Net Charge (pH 7.4) 1.25

Charge Density (pH 7.0) 0.0033

GRAVY Index-0.34

Hydrophobic Moment 0.86

Boman Index0.01

Instability Index36.39

Aliphatic Index 90.07

Aromaticity 0.0815

Extinction Coeff. Reduced 46300.00

Extinction Coeff. Oxidized 46425.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232118 VERIFIED: NO

Provenance & Taxonomy

OrganismProteus sp [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence