Peptide Database

Peptide Namecycloviolacin O1

Function Ontology

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC128H206N34O41S5

DescriptionStandard

        GIPAESCVYIPCTVTALLGCSCSNRVCYN
    

Molecular Weight3037.53 Da

Isoelectric Point (pI)5.97

Net Charge (pH 7.0)-0.29

Net Charge (pH 7.4) -0.57

Charge Density (pH 7.0) -0.0100

GRAVY Index0.69

Hydrophobic Moment 0.36

Boman Index0.24

Instability Index41.02

Aliphatic Index 90.69

Aromaticity 0.0690

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1187.53

LogP -14.40

H-bond Donors 46.0

H-bond Acceptors 46.0

Rotatable Bonds 91.0

Heavy Atoms 208.0

Ring Count 4.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0152426 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Nematocidal Anthelmintic

TargetHaemonchus contortus

Activity2.82

MethodIC50

RECORD: Rec_0260102 VERIFIED: YES