Peptide Database

Peptide NameBrevinin-2Ef

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC351H590N96O113S7

DescriptionStandard

        MFTMKKSLLLIFFLGTISLSLRQEERNADDDDGEMTEEEKRGIMDTLKNLAKTAGKGALQSLVKMASCKLSGQC
    

Molecular Weight8187.47 Da

Isoelectric Point (pI)6.20

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.78

Charge Density (pH 7.0) -0.0068

GRAVY Index-0.27

Hydrophobic Moment 0.71

Boman Index-0.05

Instability Index45.21

Aliphatic Index 84.46

Aromaticity 0.0405

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3429.76

LogP -35.88

H-bond Donors 121.0

H-bond Acceptors 120.0

Rotatable Bonds 295.0

Heavy Atoms 567.0

Ring Count 3.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0304811 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax lessonae [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Amphibian defense peptide Non-hemolytic Non-ribosomal