Peptide Database

Peptide NameM-ectatotoxin-Eb2c (M-ECTX-Eb2c) (Ponericin-Q50)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC159H241N35O35

DescriptionStandard

        FWGALFKTVAKVVAPFVPDIVKWVQEKV
    

Molecular Weight3202.83 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0629

GRAVY Index0.69

Hydrophobic Moment 0.63

Boman Index0.33

Instability Index9.20

Aliphatic Index 111.07

Aromaticity 0.1786

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1105.02

LogP -1.45

H-bond Donors 37.0

H-bond Acceptors 37.0

Rotatable Bonds 99.0

Heavy Atoms 229.0

Ring Count 9.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013733 VERIFIED: YES

Provenance & Taxonomy

OrganismEctatomma brunneum [Animal]

FamilyPonericin-Q

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli

RECORD: Rec_0170966 VERIFIED: YES

Provenance & Taxonomy

OrganismEctatomma brunneum [Animal]

FamilyPonericin-Q

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetArthrobacter globiformis

RECORD: Rec_0239653 VERIFIED: NO

Provenance & Taxonomy

OrganismEctatomma quadridens [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0288088 VERIFIED: YES

Provenance & Taxonomy

OrganismEctatomma quadridens [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli

Activity3.5 μM

MethodMIC

RECORD: Rec_0375099 VERIFIED: YES

Provenance & Taxonomy

OrganismEctatomma brunneum [Animal]

FamilyPonericin-Q

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetPseudomonas aeruginosa