Peptide Database

Peptide NamePi-phymatoxin-Pcf1a

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC140H226N46O44S7

DescriptionStandard

        CASQGQKCKTKSDCCNGMWCAGTRGHTCYKPK
    

Molecular Weight3482.03 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)4.78

Net Charge (pH 7.4) 4.43

Charge Density (pH 7.0) 0.1495

GRAVY Index-0.93

Hydrophobic Moment 0.36

Boman Index-0.24

Instability Index0.99

Aliphatic Index 6.25

Aromaticity 0.0625

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1481.05

LogP -21.61

H-bond Donors 58.0

H-bond Acceptors 57.0

Rotatable Bonds 116.0

Heavy Atoms 237.0

Ring Count 5.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0061979 VERIFIED: YES

Provenance & Taxonomy

OrganismPhymanthus crucifer [Animal]

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15, 8-20, 14-28

Bio-Activity Profile

Function

Toxin

TargetIn rat dorsal root ganglia neurons

Activity0.1 μM

MethodIC50