MYP_012916
halicylindramide C
Antimicrobial
Venom / Toxin
▸
General toxin
▸
Toxin
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
XXPVXWRXTXFTNX
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
RECORD: Rec_0316582
VERIFIED: YES
Provenance & Taxonomy
Halichondria cylindrata [Animal]
halicylindramide
Structure & Mods
side-chain cyclized peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Formylation
Non-proteinogenic/modified monomers: D-NFo-Ala; Br-Phe; t-Leu; D-CysA; NMe-Gln; NMe-Gly
Bio-Activity Profile
Antifungal
Antimicrobial
Toxin
Mortierella ramanniana
7.5 μg/disk
antifungal disk assay
RECORD: Rec_0432015
VERIFIED: YES
Provenance & Taxonomy
Halichondria cylindrata [Animal]
halicylindramide
Structure & Mods
side-chain cyclized peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Formylation
Lactonized with threonine residue
Non-proteinogenic/modified monomers reported; N-terminus formylated; C-terminus lactonized
Bio-Activity Profile
Cytotoxic
Anticancer
P388 murine leukemia cells
0.2 μg/mL
IC50