Peptide Database

Peptide NameLantibiotic Flvalpha.b

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC356H568N100O122S8

DescriptionStandard

        MNKNPIYRSEEEAKNIACGNVAAELDENSQALDAINGAGWKQTIVCTIAQGTVGCLVSYGLGNGGYCCTYTVECSKTCNK
    

Molecular Weight8457.43 Da

Isoelectric Point (pI)4.86

Net Charge (pH 7.0)-2.56

Net Charge (pH 7.4) -2.90

Charge Density (pH 7.0) -0.0320

GRAVY Index-0.21

Hydrophobic Moment 0.52

Boman Index0.05

Instability Index51.55

Aliphatic Index 72.00

Aromaticity 0.0625

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3616.83

LogP -46.38

H-bond Donors 129.0

H-bond Acceptors 128.0

Rotatable Bonds 282.0

Heavy Atoms 586.0

Ring Count 7.0

Amide Bonds 90.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0411870 VERIFIED: NO

Provenance & Taxonomy

OrganismRuminococcus flavefaciens [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Synergistic peptide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence