Peptide Database

Peptide NameMaximins 3 H3 type 1 [Cleaved into: Maximin-3; Maximin-H3]

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antiviral

Antiviral ▸ Anti-HIV

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Reproductive biology ▸ Contraceptive activity ▸ Spermicidal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC710H1173N205O218S3

DescriptionStandard

        MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEEESLREIRGIGGKILSGLKTALKGAAKELASTYLHRKRIAEDHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQEEIANLFTKKEKRILGPVLGLVGNALGGLIKKIG
    

Molecular Weight16165.35 Da

Isoelectric Point (pI)6.86

Net Charge (pH 7.0)-0.20

Net Charge (pH 7.4) -0.62

Charge Density (pH 7.0) -0.0014

GRAVY Index-0.37

Hydrophobic Moment 0.67

Boman Index-0.08

Instability Index44.27

Aliphatic Index 100.28

Aromaticity 0.0483

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6904.94

LogP -66.55

H-bond Donors 241.0

H-bond Acceptors 224.0

Rotatable Bonds 571.0

Heavy Atoms 1136.0

Ring Count 12.0

Amide Bonds 153.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0157330 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyBombinin; Maximin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Antiviral Anti-HIV Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Cytotoxic Hemolytic Spermicidal

TargetGram Negative Bacteria and Gram Positive Bacteria

RECORD: Rec_0188068 VERIFIED: NO