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MYP_012886
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Basic Information
So-D4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Plant bioactivity ▸ Plant defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
23 amino acids
C115H188N34O30S3
Standard
Sequence
MFFSSKKCKTVSKTFRGPCVRNA
Physicochemical Analysis
2623.13 Da
10.48
5.48
5.23
0.2381
-0.37
0.64
-0.19
18.42
29.57
0.1304
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1066.85
-12.47
41.0
39.0
88.0
182.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0207446 VERIFIED: YES
Provenance & Taxonomy
Leaves and stems [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperNovel defensin subfamily from spinach (Spinacia oleracea).
RECORD: Rec_0220857 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 8.7%, T 65.2%, C 26.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0299833 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0333640 VERIFIED: NO
Provenance & Taxonomy
Spinacia oleracea [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Antifungal Fungicide Plant Defense Non-hemolytic Non-ribosomal
Fusarium
Qualitative functional evidence
PMID9762899 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9762899/; https://www.uniprot.org/uniprotkb/P81569/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0336891 VERIFIED: YES
Provenance & Taxonomy
Spinacia oleracea [Plant]
Defensin
3562
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperPubMed PMID 9762899 PMID9762899 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9762899/
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