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MYP_012847
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Basic Information
Cliotide T15
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
29 amino acids
C135H217N37O40S6
Standard
Sequence
GLPICGETCFKTKCYTKGCSCSYPVCKRN
Physicochemical Analysis
3190.78 Da
8.89
3.70
3.40
0.1275
-0.26
0.32
-0.07
40.29
36.90
0.1034
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1248.52
-15.01
50.0
50.0
102.0
218.0
5.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0306703 VERIFIED: NO
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
backbone-cyclized cyclotide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperCliotide T15 (Cyclotide cT15) Evidence URLhttps://www.uniprot.org/uniprotkb/C0HJS2/entry
RECORD: Rec_0327550 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
Structure & Mods
backbone-cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
5-19; 9-21; 14-26
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
0.5 μM
MIC
RECORD: Rec_0348339 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Animal]
Cyclotide
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus (Gram-positive)
PMID27007913 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27007913/
RECORD: Rec_0371367 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Animal]
Cyclotide
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli (Gram-negative)
PMID27007913 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27007913/
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