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MYP_012823
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Basic Information
D-SMAP-29 (1-18)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
18 amino acids
C91H161N35O20
Standard
Sequence
RGLRRLGRKIAHGVKKYG
Physicochemical Analysis
2065.47 Da
12.00
6.84
6.58
0.3802
-0.98
1.07
-0.42
25.74
86.67
0.0556
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
932.59
-8.67
36.0
28.0
74.0
146.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0074355 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
20.0 μg/mL
MBC
PMID11600395;24221355;21377841 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11600395/
RECORD: Rec_0093190 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis KCTC 3068
32 μM
MIC
PMID11600395;24221355;21377841 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11600395/
RECORD: Rec_0094920 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus KCTC 1621
4 μM
MIC
PMID11600395;24221355;21377841 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11600395/
RECORD: Rec_0097271 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
APD analysis reveals this sequence is most similar (62.07%) to SMAP-29 R=G=22%; K:17%; L:11%; Mol. Wt: 3287.864; GRAVY: -0.98; Mol Formula: C91H161N35O20; mol ex coeff: 1490
Bio-Activity Profile
Antimicrobial Anticancer
Staphylococcus aureus
8 μM
MIC
PaperBacterial killing mechanism of sheep myeloid antimicrobial peptide-18 (SMAP-18) and its Trp-substituted analog with improved cell selectivity and reduced mammalian cell toxicity.
RECORD: Rec_0098567 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis var. niger ATCC 9372
50.0
MIC
PMID11600395;24221355;21377841 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11600395/
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