Peptide Database

Peptide NameNeurotoxin PKTx21C2

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC139H220N44O45S8

DescriptionStandard

        AFCKYNGEQCTSDGQCCNGRCRTAFMGKICMG
    

Molecular Weight3484.02 Da

Isoelectric Point (pI)8.34

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.45

Charge Density (pH 7.0) 0.0543

GRAVY Index-0.34

Hydrophobic Moment 0.23

Boman Index-0.08

Instability Index14.31

Aliphatic Index 18.44

Aromaticity 0.0938

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1469.14

LogP -20.65

H-bond Donors 57.0

H-bond Acceptors 55.0

Rotatable Bonds 117.0

Heavy Atoms 236.0

Ring Count 3.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077431 VERIFIED: NO

Provenance & Taxonomy

OrganismPhoneutria keyserlingi,Ctenus keyserlingii [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-17; 10-21; 16-30

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0090022 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic