Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC356H592N108O102S8

DescriptionStandard

        MRIPVLLLAISLLLSQDLPARSELEVDRICGYGTARCRRKCQSQEYRIGRCPNTSACCLKKWSDSLLNYMKH
    

Molecular Weight8273.69 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.53

Net Charge (pH 7.4) 5.16

Charge Density (pH 7.0) 0.0768

GRAVY Index-0.23

Hydrophobic Moment 0.56

Boman Index-0.12

Instability Index57.78

Aliphatic Index 94.86

Aromaticity 0.0556

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3428.81

LogP -34.17

H-bond Donors 129.0

H-bond Acceptors 117.0

Rotatable Bonds 279.0

Heavy Atoms 574.0

Ring Count 9.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177519 VERIFIED: NO

Provenance & Taxonomy

OrganismPropithecus coquereli [Bacterium]

FamilyDefensin

Tax ID379532

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence