Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC501H827N141O141S10

DescriptionStandard

        MKAFLLTLAALVLLSQVTLGSAEKCWNLRGSCREKCIKNEKLYIFCTSGKLCCLKPKFQPNMLQRNRKDNPKICLEPQKILNIQSNLDKEEQSWKHCTS
    

Molecular Weight11402.44 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)8.51

Net Charge (pH 7.4) 8.10

Charge Density (pH 7.0) 0.0860

GRAVY Index-0.38

Hydrophobic Moment 0.48

Boman Index-0.10

Instability Index51.68

Aliphatic Index 88.69

Aromaticity 0.0606

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4627.41

LogP -43.77

H-bond Donors 165.0

H-bond Acceptors 161.0

Rotatable Bonds 396.0

Heavy Atoms 793.0

Ring Count 13.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0139457 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris (Dog) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin