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MYP_012726
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Basic Information
citropin 1.1 from Australian frog
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
17 amino acids
C78H133N19O21
Standard
Sequence
GLFDVIKKVASVIGGLG
Physicochemical Analysis
1673.00 Da
8.59
0.76
0.55
0.0447
1.18
0.64
0.46
13.94
148.82
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
638.49
-4.18
22.0
22.0
57.0
118.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0186089 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea; Litoria raniformis [Animal]
Aurein
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperRozek T., Wegener K., Bowie J., Olver I. N., Carver J. A., Wallace J. C., Tyler M. J.. The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis. Eur. J. Biochem, 267, 5330-5341. PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
RECORD: Rec_0291386 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea; Litoria raniformis [Animal]
Aurein
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperRozek T., Wegener K., Bowie J., Olver I. N., Carver J. A., Wallace J. C., Tyler M. J.. The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis. Eur. J. Biochem, 267, 5330-5341. PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
RECORD: Rec_0314331 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
PaperDoyle J., Llewellyn L. E., Brinkworth C. S., Bowie J. H., Wegener K. L., Rozek T., Wabnitz P. A., Wallace J. C., Tyler M. J.. Amphibian peptides that inhibit neuronal nitric oxide synthase. Isolation of lesuerin from the skin secretion of the Australian Stony Creek frog Litoria lesueuri. Eur. J. Biochem., 269, 100-109, 2002.