Peptide Database

Peptide NameBrachyin

Function Ontology

Anticancer

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC215H309N57O64S6

DescriptionStandard

        CLGENVPCDKDRPNCCSRYECLEPTGYGWWYASYYCYKKRS
    

Molecular Weight4908.49 Da

Isoelectric Point (pI)7.74

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.39

Charge Density (pH 7.0) 0.0171

GRAVY Index-0.97

Hydrophobic Moment 0.32

Boman Index-0.19

Instability Index65.64

Aliphatic Index 28.54

Aromaticity 0.1951

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1971.27

LogP -18.48

H-bond Donors 76.0

H-bond Acceptors 71.0

Rotatable Bonds 150.0

Heavy Atoms 342.0

Ring Count 13.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0102808 VERIFIED: YES

Provenance & Taxonomy

OrganismBrachypelma albopilosum [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermC-terminal amidation

DisulfideThree disulfide bonds reported, sites unresolved

Bio-Activity Profile

Function

Anticancer Neurotoxin Insecticidal Analgesic

TargetMolt-4; C8166; BIU-87; T24; A549; Calu-6

MethodMTT cell proliferation/cytotoxicity assay

RECORD: Rec_0431995 VERIFIED: YES