Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length221 amino acids

Chemical FormulaC1111H1705N255O343S9

DescriptionStandard

        QVDDLAEVDYSLSSLPAVFRPFIDLDLKGIVFPTGNYTDSPYVPASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNINTEIFGTIIPEVAKYSVTPNPVMLKLMATEIPIISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNIFDQKLMGSLCLNRLQFSLAHSNVGSFEVLLLENILSYILQTEVIPSANGK
    

Molecular Weight24410.51 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-17.14

Net Charge (pH 7.4) -17.47

Charge Density (pH 7.0) -0.0776

GRAVY Index0.29

Hydrophobic Moment 0.60

Boman Index0.23

Instability Index43.33

Aliphatic Index 99.28

Aromaticity 0.1176

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0288341 VERIFIED: NO

Provenance & Taxonomy

OrganismEdolisoma coerulescens [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria