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MYP_012613
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Basic Information
buCATHL4D
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Standard
18 amino acids
C130H167N35O19
Standard
Sequence
RIRFPWPWRWPWWPPFRG
Physicochemical Analysis
2523.94 Da
12.00
3.76
3.56
0.2089
-1.16
0.33
-0.07
63.85
21.67
0.3889
27500.00
27500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
840.62
2.01
31.0
23.0
62.0
184.0
17.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003409 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus NCDC-0111
12.5 μM
MIC
PaperDiversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins.
RECORD: Rec_0053277 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0074308 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus cereus NCDC-0240
1.5 μM
MIC
PaperDiversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins.
RECORD: Rec_0093160 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 29213
6 μM
MIC
PaperDiversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins.
RECORD: Rec_0139715 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Salmonella Typhimurium ATCC-14028
50 μM
MIC
PaperDiversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins.
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