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MYP_012598
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Enzyme modulation ▸ Enzyme inhibition ▸ Phosphodiesterase inhibition ▸ CaMPDE inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
25 amino acids
C149H232N38O33S
Standard
Sequence
VYQHQKAMKPWIQPKTKVIPYVRYL
Physicochemical Analysis
3115.74 Da
10.12
4.81
4.54
0.1926
-0.60
0.46
-0.05
2.56
85.60
0.1600
9970.00
9970.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1155.99
-4.08
39.0
40.0
98.0
221.0
9.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0071595 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S2-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli; Bacillus cereus; Listeria innocua; Micrococcus flavus
99 μM
MIC
PaperIdentification of two distinct antibacterial domains within the sequence of bovine αs2-casein | Recio, I. et al. | DOI: 10.1016/s0304-4165(99)00079-3 Evidence URLhttps://www.uniprot.org/uniprotkb/P02663/entry
RECORD: Rec_0152918 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. sakazakii
PMID23793637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23793637/
RECORD: Rec_0153384 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S2-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli; Bacillus subtilis; Listeria monocytogenes; Listeria innocua
MIC
PaperIsolation and characterisation of a novel antibacterial peptide from bovine αS1-casein | McCann, KB. et al. | DOI: 10.1016/j.idairyj.2005.05.005 Evidence URLhttps://www.uniprot.org/uniprotkb/P02663/entry
RECORD: Rec_0184448 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus subtilis
21 μM
MIC
RECORD: Rec_0202087 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes
PMID23793637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23793637/
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