Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length440 amino acids

Chemical FormulaC2228H3539N605O622S8

DescriptionStandard

        AHQQGIAILEKELAQLKLPDISGDSRVGRVGKVRYELSRLRLRDFHLPYSRITPISNVGLQISISNAFAELDGDWRVKFLFVRAHGSFNLKVENVYIKISLRLGSDATGKPTVSTSECSARISQVRVLFSGKLGWLYNLFHRAIESRFRKILEDKVCGIVDRSVRNELQTYVQTLPVTARIDAKTGIDYSLVAPPRATTQSLDADLKGEFYSLAHRSTVPFSPLPLAFPSDHDRMVYFGASSYFFNTAGIAYHEAGALVFEITEDMIPKDAAFHLDTSILSVFIPQLEEMYPNMPVKFRLSTPTAPFLTIGPGGISLKPIVDAQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGTFKVRTMQSLMNFLTSTILLPRLNARLDEGFPLPLPDRIQLSNILVRFYQNFLLLGADVHFQPR
    

Molecular Weight49009.13 Da

Isoelectric Point (pI)9.58

Net Charge (pH 7.0)11.60

Net Charge (pH 7.4) 10.84

Charge Density (pH 7.0) 0.0264

GRAVY Index0.08

Hydrophobic Moment 0.71

Boman Index0.08

Instability Index32.65

Aliphatic Index 105.25

Aromaticity 0.0932

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018415 VERIFIED: NO

Provenance & Taxonomy

OrganismStruthidea cinerea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria