Peptide Database

Peptide NameCaerin-1.1 [Cleaved into: Caerin-1.1.1; Caerin-1.1.2; Caerin-1.1.4]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC363H588N96O120S2

DescriptionStandard

        MASLKKSLFLVLLLGFVSVSICEEEKRQEDEDEHEEEGESQEEGSEEKRGLLSVLGSVAKHVLPHVVPVIAEHLG
    

Molecular Weight8281.25 Da

Isoelectric Point (pI)4.66

Net Charge (pH 7.0)-10.12

Net Charge (pH 7.4) -10.59

Charge Density (pH 7.0) -0.1350

GRAVY Index-0.21

Hydrophobic Moment 0.50

Boman Index0.03

Instability Index69.25

Aliphatic Index 106.40

Aromaticity 0.0267

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3449.88

LogP -30.77

H-bond Donors 117.0

H-bond Acceptors 116.0

Rotatable Bonds 289.0

Heavy Atoms 581.0

Ring Count 8.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0375176 VERIFIED: YES

Provenance & Taxonomy

OrganismRanoidea caerulea [Animal]

FamilyFrog skin active peptide (FSAP); Caerin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Non-hemolytic

TargetNo Target Organism Found