Peptide Database

Peptide NameHuman beta defensin 3

Function Ontology

—

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC172H290N56O52S4

DescriptionStandard

        GIINTLQRYYCRIRSGRCAVLSCLPKEEQIGRCSSAG
    

Molecular Weight4102.75 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)3.72

Net Charge (pH 7.4) 3.45

Charge Density (pH 7.0) 0.1006

GRAVY Index-0.17

Hydrophobic Moment 0.75

Boman Index-0.11

Instability Index65.57

Aliphatic Index 87.03

Aromaticity 0.0541

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1783.13

LogP -21.55

H-bond Donors 69.0

H-bond Acceptors 60.0

Rotatable Bonds 138.0

Heavy Atoms 284.0

Ring Count 3.0

Amide Bonds 39.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0064345 VERIFIED: YES

Provenance & Taxonomy

OrganismLeptonychotes weddellii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)