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MYP_012530
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Basic Information
Pelteobagrin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C108H182N26O25
Standard
Sequence
GKLNLFLSRLEILKLFVGAL
Physicochemical Analysis
2244.76 Da
9.99
1.76
1.55
0.0880
1.09
0.42
0.33
12.92
175.50
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
830.78
-2.34
29.0
27.0
78.0
159.0
2.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0219718 VERIFIED: YES
Provenance & Taxonomy
Pelteobagrus fulvidraco [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
64 μg/mL
MIC
RECORD: Rec_0238416 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0240200 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Rabbit erythrocytes
400 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/21073979/ PMID21073979 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21073979/
RECORD: Rec_0307274 VERIFIED: YES
Provenance & Taxonomy
Yellow catfish [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
as well as fungi, including Staphylococcus aureus ATCC 6538, Bacillus subtilis ATCC 6633
2-4 μM
MIC
PaperIsolation and identification of pelteobagrin, a novel antimicrobial peptide from the skin mucus of Yellow catfish (Pelteobagrus fulvidraco)
RECORD: Rec_0372199 VERIFIED: YES
Provenance & Taxonomy
Actinopterygii [Animal]
7898
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21950656 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21950656/
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