Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length252 amino acids

Chemical FormulaC1283H1975N297O382S9

DescriptionStandard

        KIISVGFLIFSVLSTTLTAVMQIDDLAEVDYSLSSLPAVFQPFIDLDLKGTVFPAGNYTDSPYMAASFTIPEQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTITEEVSRTQRYGLRTCRYFNINTEIFSSIIPEVAKYSVTPYPVMLKLMSTEVPVISLQQDAFTVEIQGSVEVLAILPDSTTWSLFTLNVAANTSISLNIFDQKLMGSLCLNRIQFSLAHSSVGFFEVLLLENILSYILQAEVIPSANGK
    

Molecular Weight27960.75 Da

Isoelectric Point (pI)4.33

Net Charge (pH 7.0)-12.14

Net Charge (pH 7.4) -12.48

Charge Density (pH 7.0) -0.0482

GRAVY Index0.40

Hydrophobic Moment 0.78

Boman Index0.25

Instability Index44.16

Aliphatic Index 103.29

Aromaticity 0.1270

Extinction Coeff. Reduced 23380.00

Extinction Coeff. Oxidized 23505.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177185 VERIFIED: NO

Provenance & Taxonomy

OrganismChloropsis hardwickii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria