Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC375H609N111O109S8

DescriptionStandard

        MRKTLKRFKTEELTKCYQGYGVCRERCRKDETEVHFCGNNRRCCINSDSTILTRVVVKDIVWSKVITTSMPFY
    

Molecular Weight8673.05 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)6.54

Net Charge (pH 7.4) 6.16

Charge Density (pH 7.0) 0.0895

GRAVY Index-0.53

Hydrophobic Moment 0.60

Boman Index-0.22

Instability Index38.43

Aliphatic Index 65.21

Aromaticity 0.0959

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3645.75

LogP -37.37

H-bond Donors 139.0

H-bond Acceptors 125.0

Rotatable Bonds 295.0

Heavy Atoms 603.0

Ring Count 10.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0088530 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus dingo [Animal]

FamilyDefensin

Tax ID286419

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

RECORD: Rec_0403935 VERIFIED: NO