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MYP_012438
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Basic Information
Caerin 1.20
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C124H200N32O29
Standard
Sequence
GLFGILGSVAKHVLPHVIPVVAEHL
Physicochemical Analysis
2603.11 Da
7.02
0.02
-0.33
0.0009
1.18
0.42
0.52
25.15
159.60
0.0400
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
913.73
-3.34
30.0
32.0
80.0
185.0
6.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0069825 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]; Litoria caerulea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
MIC 25-50 ug/ml, Staphylococcus epidermidis
25 μg/mL
MIC
PaperHost-defence peptide profiles of the skin secretions of interspecific hybrid tree frogs and their parents, female Litoria splendida and male Litoria caerulea.
RECORD: Rec_0075803 VERIFIED: YES
Provenance & Taxonomy
Magnificent tree [Animal]
Caerin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID16824041 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16824041/
RECORD: Rec_0084003 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 32.0%, E 0.0%, T 32.0%, C 36.0% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Antiviral Antimicrobial Anti-Gram-positive
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0089377 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]; Litoria caerulea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Enterococcus faecalis
>100 μg/mL
MIC
PaperHost-defence peptide profiles of the skin secretions of interspecific hybrid tree frogs and their parents, female Litoria splendida and male Litoria caerulea.
RECORD: Rec_0103722 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]; Litoria caerulea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Escherichia coli
>100 μg/mL
MIC
PaperHost-defence peptide profiles of the skin secretions of interspecific hybrid tree frogs and their parents, female Litoria splendida and male Litoria caerulea.
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