Peptide Database

Peptide NameBradykinin-potentiating peptide 2

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Membrane / Ion-channel modulation ▸ Ion channel modulation

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC67H95N19O14

DescriptionStandard

        QKPWPPGHHIPP
    

Molecular Weight1390.59 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)0.93

Net Charge (pH 7.4) 0.63

Charge Density (pH 7.0) 0.0778

GRAVY Index-1.55

Hydrophobic Moment 0.34

Boman Index0.01

Instability Index66.80

Aliphatic Index 32.50

Aromaticity 0.0833

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 481.73

LogP -2.01

H-bond Donors 13.0

H-bond Acceptors 17.0

Rotatable Bonds 33.0

Heavy Atoms 100.0

Ring Count 9.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0171531 VERIFIED: YES

Provenance & Taxonomy

OrganismLachesis muta muta [Animal]

FamilyBradykinin-potentiating peptide

Tax ID8753

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Enzyme modulation Ion channel modulation ACE inhibitory

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0378271 VERIFIED: YES