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MYP_012423
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Basic Information
Pepthiomycin A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
12 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
NXTAVAILAXLE
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0255578 VERIFIED: YES
Provenance & Taxonomy
Hirsutella nivea [Fungus]
Nonribosomal peptide
Structure & Mods
branched peptide architecture [Branched]
all-D amino-acid peptide [D]
None
None
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis H37Rv
MIC
PMID25681127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25681127/
RECORD: Rec_0256674 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Natural peptide
9913
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium R1Rv attenuated human
MIC
PMID13118063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/13118063/
RECORD: Rec_0263077 VERIFIED: YES
Provenance & Taxonomy
Actinoplanes awajinensis [Bacterium]
Nonribosomal peptide
Structure & Mods
branched peptide architecture [Branched]
all-D amino-acid peptide [D]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis Rv
IC50
PMID25681127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25681127/
RECORD: Rec_0285384 VERIFIED: YES
Provenance & Taxonomy
Trichoderma sp. [Fungus]
Natural peptide
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium bovis BCG (aerobic)
MIC
PMID20483615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20483615/
RECORD: Rec_0295662 VERIFIED: YES
Provenance & Taxonomy
Streptomyces sp. [Bacterium]
Natural peptide
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis 607
MIC
PMID5459623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5459623/
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