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MYP_012423
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Basic Information
Pepthiomycin A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
12 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
NXTAVAILAXLE
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0052750 VERIFIED: YES
Provenance & Taxonomy
Streptomyces griseus [Bacterium]
Nonribosomal peptide
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial Antifungal
Mycobacterium avium IFO 3
MIC
PMID4630599 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4630599/
RECORD: Rec_0055524 VERIFIED: YES
Provenance & Taxonomy
Streptomyces sioyaensis [Bacterium]
Natural peptide
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis
PMID4630599 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4630599/
RECORD: Rec_0067464 VERIFIED: YES
Provenance & Taxonomy
Trichoderma sp. [Fungus]
Natural peptide
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis H37Rv (aerobic)
MIC
PMID20483615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20483615/
RECORD: Rec_0075106 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Nonribosomal peptide
1423
Structure & Mods
branched peptide architecture [Branched]
all-D amino-acid peptide [D]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis H37Rv
MIC
PMID25681127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25681127/
RECORD: Rec_0083063 VERIFIED: YES
Provenance & Taxonomy
Trichoderma sp. [Fungus]
Natural peptide
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacteria smegmatis (aerobic)
MIC
PMID20483615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20483615/
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