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MYP_012423
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Basic Information
Pepthiomycin A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
12 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
NXTAVAILAXLE
Physicochemical Analysis
0.00 Da
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0.00
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0355832 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Natural peptide
32630
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis Ra 7632G
MIC
PMID8641802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8641802/
RECORD: Rec_0361630 VERIFIED: YES
Provenance & Taxonomy
Nocardia sp. [Bacterium]
Natural peptide
Structure & Mods
branched peptide architecture [Branched]
noncanonical stereochemical modification [Modified]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium pneumoniae
MIC
PMID25681127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25681127/
RECORD: Rec_0369261 VERIFIED: YES
Provenance & Taxonomy
Bacillus polymyxa [Bacterium]
Nonribosomal peptide
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis 607
10 μg/mL
MIC
PMID5042449 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5042449/
RECORD: Rec_0393906 VERIFIED: YES
Provenance & Taxonomy
Lyngbya majuscula [Bacterium]
Natural peptide
Structure & Mods
branched peptide architecture [Branched]
all-D amino-acid peptide [D]
Non-standard residues/chemistry in sequence: NOTAVAILABLE
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacteria smegmatis ATCC 35818
MIC
PMID25681127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25681127/
RECORD: Rec_0405919 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID23085771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23085771/
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