MYP_012418
Ovine Brain natriuretic peptide (oBNP)
Binding / Molecular interaction
▸
Binding activity
Cardiovascular
Enzyme modulation
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Enzyme inhibition
▸
ACE inhibition
▸
ACE inhibitory
Hormonal / Endocrine
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Hormone peptide
Regulatory peptide
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Biological modulation
Standard
29 amino acids
C136H230N48O39S4
Standard
MMRDSGCFGRRLDRIGSLSGLGCNVLRRY
3289.84 Da
10.62
3.48
3.23
0.1201
-0.27
0.78
-0.20
53.65
77.24
0.0690
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1448.13
-17.05
57.0
47.0
113.0
227.0
2.0
29.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0136325
VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Natriuretic peptide
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Receptor-binding
receptor binding
Kd
Infused in pulmonary artery of sheep, in vivo; 156 s
RECORD: Rec_0274451
VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Brain natriuretic peptide
9940
Structure & Mods
linear peptide with reported disulfide constraint [Linear]
canonical L-amino-acid peptide [L]
7-23
Bio-Activity Profile
Hormone
Endocrine
Receptor modulation
ACE inhibitory
Experimental: 3.1 minutes; /186 seconds; Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0382671
VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]
Natriuretic peptide
9940
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-23
Bio-Activity Profile
Hormone
Cardiovascular