Peptide Database

Peptide NameHLP1 (Lactotransferrin truncated peptide)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC88H140N30O21S

DescriptionStandard

        FQWQRNMRKVRGPPVS
    

Molecular Weight1986.31 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2349

GRAVY Index-1.26

Hydrophobic Moment 0.60

Boman Index-0.39

Instability Index25.84

Aliphatic Index 36.25

Aromaticity 0.1250

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 859.25

LogP -8.34

H-bond Donors 30.0

H-bond Acceptors 26.0

Rotatable Bonds 63.0

Heavy Atoms 140.0

Ring Count 5.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0150581 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyLactoferricin

Tax ID9606

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli NCTC 8007

Activity500 μM

MethodMIC

RECORD: Rec_0164584 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTransferrin

Tax ID9606

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetRefer PubMed ID 14573629 :- Streptococcus mutans, Vibrio cholerae, Pseudomonas aeruginosa, Candida albicans, Human papillomavirus] [Refer PubMed ID 9596699 :- Staphylococcus aureus NCTC 10571

Activity500 μM

MethodMIC

RECORD: Rec_0271461 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyLactoferrin-derived

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorescein/FITC labeling

C-TermAmidation

Other ModsN-term detail: Labelled with fluoresceine

Bio-Activity Profile

Function

Cell-penetrating peptide Antimicrobial

TargetHeLa

MethodFluorescence-based uptake assay

RECORD: Rec_0301593 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyLactoferricin

Tax ID9606

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetClinical isolates: Acinetobacter sp

RECORD: Rec_0307052 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTransferrin

Tax ID9606

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetRefer PubMed ID 14573629 :- Streptococcus mutans, Vibrio cholerae, Pseudomonas aeruginosa, Candida albicans, Human papillomavirus] [Refer PubMed ID 9596699 :- Staphylococcus aureus NCTC 10571

Activity1000 μM

MethodMIC

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