Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC367H605N105O107S8

DescriptionStandard

        MKLFLLVLTVSLVLAQVTSVMKCWGKSGRCRTTCKNGEVFHILCNVETKCCVQQKYVHFRVEASNTTRSLGSTSAD
    

Molecular Weight8456.89 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.62

Net Charge (pH 7.4) 5.20

Charge Density (pH 7.0) 0.0740

GRAVY Index0.15

Hydrophobic Moment 0.64

Boman Index0.03

Instability Index16.35

Aliphatic Index 88.29

Aromaticity 0.0658

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3454.11

LogP -37.95

H-bond Donors 130.0

H-bond Acceptors 123.0

Rotatable Bonds 286.0

Heavy Atoms 587.0

Ring Count 8.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010788 VERIFIED: NO

Provenance & Taxonomy

OrganismTrichechus manatus latirostris [Bacterium]

FamilyDefensin

Tax ID127582

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence