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MYP_012361
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Basic Information
Transportan-PKI
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
38 amino acids
C184H311N53O48
Standard
Sequence
AGYLLGKINLKALAALAKKILTYADFIASGRTGRRNAI
Physicochemical Analysis
4033.76 Da
10.64
5.79
5.59
0.1524
0.32
0.58
0.11
21.73
123.68
0.0789
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1654.43
-14.09
60.0
54.0
138.0
285.0
3.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021694 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine B
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID15937518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15937518/
RECORD: Rec_0178614 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine-labelled
None
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0207968 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine B
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID15937518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15937518/
RECORD: Rec_0315490 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Transportan/TP10
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorophore labeling
None
N-term detail: Rhodamine-labelled
Bio-Activity Profile
Cell-penetrating peptide
CHO K1; HeLa; A549 cells
Fluorescence-based uptake assay
PMID15937518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15937518/
RECORD: Rec_0361470 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Transportan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine conjugation
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID15937518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15937518/
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