Peptide Database

Peptide Nameneutrophil defensin 4-like

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC424H697N133O140S8

DescriptionStandard

        MRTLALLAALLLLALQAQAGPLQERDDEAPAQEQPETEDQDMAISFAGDESSGARASGSARALTCACRRTRCRSSERVSGTCLYRGVPYLFCCR
    

Molecular Weight10154.40 Da

Isoelectric Point (pI)5.36

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.86

Charge Density (pH 7.0) -0.0163

GRAVY Index-0.25

Hydrophobic Moment 0.67

Boman Index-0.10

Instability Index60.86

Aliphatic Index 76.06

Aromaticity 0.0426

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4424.95

LogP -55.27

H-bond Donors 163.0

H-bond Acceptors 147.0

Rotatable Bonds 337.0

Heavy Atoms 705.0

Ring Count 8.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400103 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrocebus murinus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Fungicidal

MethodQualitative functional evidence