Peptide Database

Peptide NameBovine Beta-defensin 11

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC100H174N36O29S5

DescriptionStandard

        PVSCARNKGICVPSRCPGNMRQM
    

Molecular Weight2505.00 Da

Isoelectric Point (pI)9.83

Net Charge (pH 7.0)3.93

Net Charge (pH 7.4) 3.83

Charge Density (pH 7.0) 0.1708

GRAVY Index-0.40

Hydrophobic Moment 0.45

Boman Index-0.18

Instability Index72.01

Aliphatic Index 46.52

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1053.40

LogP -14.64

H-bond Donors 40.0

H-bond Acceptors 38.0

Rotatable Bonds 81.0

Heavy Atoms 170.0

Ring Count 3.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204600 VERIFIED: YES

Provenance & Taxonomy

OrganismBubalus bubalis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)